Витамин D: роль в спорте и спортивной медицине (обзор литературы)
DOI:
https://doi.org/10.32652/olympic2017.1_%25xКлючевые слова:
Спорт, физические нагрузки, витамин D, дефицит, недостаточность, нутритивно-метаболическая поддержкаАннотация
Детально описана роль витамина D в стимуляции работоспособности и поддержании здоровья спортсменов. Обоснованы критерии дефицита и пути коррекции уровня этого витамина в организме. Приведены основные фармакологические субстанции на основе витамина D, рекомендованные для употребления представителям разных видов спорта на этапах годичного цикла подготовки. В обзорной работе приведены систематизированные данные относительно методологии оценки содержания и критериев недостаточности и дефицита витамина D у представителей разных видов спорта, проживающих в разных климатических зонах. Сформулировано, что эффекты витамина D можно условно разделить на специальные, определяющие прямое и опосредованное влияние на показатели физической подготовленности и работоспособности спортсменов, и защитные, заключающиеся в повышении устойчивости к инфекционным болезням, в нормализации обменных процессов и предупреждении различных обменных заболеваний спортсменов. Постулировано, что у представителей России, Украины, Беларуси, а также западных стран наблюдаются частые признаки дефицита этого витамина, что сопровождается не только снижением эффективности тренировочной деятельности, но и приводит к развитию вторичных дизиммунных реакций, снижению минерализации костной ткани и росту травматизма. Описаны препараты и диетические добавки витамина D, а также их дозировки, рекомендованные мировыми ведущими спортивными институтами для применения у спортсменов на разных этапах годичного макроцикла. Обсуждены также механизмы влияния дефицита витамина D на образование в организме эндогенного тестостерона.Библиографические ссылки
Drygina LB, Dorofeichik-Drygina NA, Prokhorova OV. Vitamin D status in the formation of bone defi cit in fi refi ghters of Emergencies Ministry of Russia. Medico-Biological and Socio-Psychological Problems in Emergency Situations. 2013;3:5-9.
Karonova TL, Grineva EN, Nikitina IL, et al. The prevalence of vitamin D defi ciency in the Northwest region of the Russian Federation among the residents of St. Petersburg and Petrozavodsk. Osteoporoz i osteopatii. 2013;3:3–7.
Clinical recommendations «Vitamin D defi ciency in adults. Diagnosis, treatment and prevention». Russian Association of endocrinologists, FSBI «Endocrinology Research Center of Ministry of Healthcare of the Russian Federation». Moscow; 2015.
Markova TN, Markov DS, Markelova TN, et al. The prevalence of vitamin D defi ciency and risk factors for osteoporosis in young age people. Vestnik Chuvashskogo Universiteta. 2012;3:441–446.
Ardestani A, Parker B, Mathur S, Clarkson P, Pescatello L, Hoff man H et al. Relation of Vitamin D Level to Maximal Oxygen Uptake in Adults. The American Journal of Cardiology. 2011;107(8):1246–1249.
Australian Sports Institute an Initiative of AIS Sports Nutrition. «Calcium Supplement» [Internet]. Available from: http://www.ausport.gov.au/__data/assets/pdf_fi le/0009/ 656289/CORP_33413_SSF_Calcium_Supplement_FS.pdf
Barker T, Schneider E, Dixon B, Henriksen V, Weaver L. Supplemental vitamin D enhances the recovery in peak isometric force shortly after intense exercise. Nutrition & Metabolism. 2013;10(1):69.
Beaudart C, Buckinx F, Rabenda V, Gillain S, Cavalier E, Slomian J et al. The Eff ects of Vitamin D on Skeletal Muscle Strength, Muscle Mass, and Muscle Power: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. The Journal of Clinical Endocrinology & Metabolism. 2014;99(11):4336-4345.
Bendik I, Friedel A, Roos F, Weber P, Eggersdorfer M. Vitamin D: a critical and essential micronutrient for human health. Frontiers in Physiology. 2014;5.
Binkley NC, Krueger DC, Kawahara TN et al. A high phylloquinone intake is required to achieve maximal osteocalcin γ-carboxylation. Am. J. Clin. Nutr. 2002;76:1055–1060.
Bischoff H, Borchers M, Gudat F et al. In situ detection of 1,25-dihydroxyvitamin D3 receptor in human skeletal muscle tissue. Histochem J. 2001;33:19–24.
Blomberg JM, Nielsen JE, Jørgensen A et al. Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract. Hum. Reprod. 2010;25:1303–1311.
Blomberg Jensen M, Dissing S. Non-genomic eff ects of vitamin D in human spermatozoa. Steroids. 2012;77(10):903-909.
Campbell P, Allain T. Muscle Strength and Vitamin D in Older People. Gerontology. 2006;52(6):335-338.
Cannell JJ, Hollis BW, Sorenson MB et al. Athletic performance and vitamin D. Med. Sci. Sports Exerc. 2009;41(5):1102–1110.
Ceglia L, Niramitmahapanya S, da Silva Morais M, Rivas D, Harris S, Bischoff -Ferrari H et al. A Randomized Study on the Eff ect of Vitamin D3Supplementation on Skeletal Muscle Morphology and Vitamin D Receptor Concentration in Older Women. The Journal of Clinical Endocrinology & Metabolism. 2013;98(12):E1927-E1935.
Chiang C, Ismaeel A, Griffi s R, Weems S. Eff ects of Vitamin D Supplementation on Muscle Strength in Athletes A Systematic Review. Journal of Strength and Conditioning Research. 2016;:1.
Close GL, Leckey J, Patterson M et al. The eff ects of vitamin D3supplementation on serum total 25(OH) D concentration and physical performance: a randomised dose-response study. Br. J. Sports Med. 2013a;47:692–696.
Close G, Russell J, Cobley J, Owens D, Wilson G, Gregson W et al. Assessment of vitamin D concentration in non-supplemented professional athletes and healthy adults during the winter months in the UK: implications for skeletal muscle function. Journal of Sports Sciences. 2013;31(4):344-353.
Close GL. Vitamin D Measurement and supplementation: what, when, why and how?. Proceedings of the Sports Science Exchange of the Research Institute for Sports and Exercise Sciences; 2015; Liverpool. Liverpool, United Kingdom: Liverpool John Moores University; 2015;28(147):1–4.
Constantini N, Arieli R, Chodick G, Dubnov-Raz G. High Prevalence of Vitamin D Insuffi ciency in Athletes and Dancers. Clinical Journal of Sport Medicine. 2010;20(5):368-371.
Dahlquist D, Dieter B, Koehle M. Plausible ergogenic eff ects of vitamin D on athletic performance and recovery. Journal of the International Society of Sports Nutrition. 2015;12(1).
Jong N, Chin A, Paw MJ et al. Functional biochemical and nutrient indices in frail elderly people are partly aff ected by dietary supplements but not by exercise. J Nutr. 1999;129(11):2028–2036.
Demay M. Mechanism of Vitamin D Receptor Action. Annals of the New York Academy of Sciences. 2006;1068(1):204-213.
Dietary Reference Intakes for Calcium and Vitamin D. Washington, USA: Institute of Medicine, National Academy of Science; 2011.
Dowd P, Hershline R, Ham S, Naganathan S. Mechanism of action of vitamin K. Natural Product Reports. 1994;11:251.
Farrokhyar F, Tabasinejad R, Dao D, Peterson D, Ayeni O, Hadioonzadeh R et al. Prevalence of Vitamin D Inadequacy in Athletes: A Systematic-Review and Meta-Analysis. Sports Medicine. 2014;45(3):365-378.
Fitzgerald J, Peterson B, Warpeha J, Wilson P, Rhodes G, Ingraham S. Vitamin D Status and V[Combining Dot Above]O2peak During a Skate Treadmill Graded Exercise Test in Competitive Ice Hockey Players. Journal of Strength and Conditioning Research. 2014;28(11):3200-3205.
Forney L, Earnest C, Henagan T, Johnson L, Castleberry T, Stewart L. Vitamin D Status, Body Composition, and Fitness Measures in College-Aged Students. Journal of Strength and Conditioning Research. 2014;28(3):814-824.
Garcia L, Ferrini M, Norris K, Artaza J. 1,25(OH)2vitamin D3enhances myogenic diff erentiation by modulating the expression of key angiogenic growth factors and angiogenic inhibitors in C2C12 skeletal muscle cells. The Journal of Steroid Biochemistry and Molecular Biology. 2013;133:1-11.
Garcia L, King K, Ferrini M, Norris K, Artaza J. 1,25(OH)2Vitamin D3Stimulates Myogenic Diff erentiation by Inhibiting Cell Proliferation and Modulating the Expression of Promyogenic Growth Factors and Myostatin in C2C12Skeletal Muscle Cells. Endocrinology. 2011;152(8):2976-2986.
Gregory S. Changes in Vitamin D are Not Associated with Changes in Cardiorespiratory Fitness. Clinical Medicine Research. 2013;2(4):68.
Hamidi M, Cheung A. Vitamin K and musculoskeletal health in postmenopausal women. Molecular Nutrition & Food Research. 2014;58(8):1647-1657.
Hamilton B, Grantham J, Racinais S, Chalabi H. Vitamin D defi ciency is endemic in Middle Eastern sportsmen. Public Health Nutrition. 2010;13(10):1528-1534.
He C, Fraser W, Tang J, Brown K, Renwick S, Rudland-Thomas J et al. The eff ect of 14 weeks of vitamin D3supplementation on antimicrobial peptides and proteins in athletes. Journal of Sports Sciences. 2015;34(1):67-74.
Heaney R, Recker R, Grote J, Horst R, Armas L. Vitamin D3 is More Potent Than Vitamin D2 in Humans. Endocrine Reviews. 2011;32(1):155-155.
Herbst K, Bhasin S. Testosterone action on skeletal muscle. Current Opinion in Clinical Nutrition and Metabolic Care. 2004;7(3):271-277.
Holick M. Vitamin D: a D-Lightful health perspective. Nutrition Reviews. 2008;66:S182-S194.
Holick M, Binkley N, Bischoff -Ferrari H, Gordon C, Hanley D, Heaney R et al. Evaluation, Treatment, and Prevention of Vitamin D Defi ciency: an Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism. 2011;96(7):1911-1930.
Iwamoto J. Vitamin K2Therapy for Postmenopausal Osteoporosis. Nutrients. 2014;6(5):1971-1980.
Jastrzębski Z. Eff ect of vitamin D supplementation on the level of physical fi tness and blood parameters of rowers during the 8-week high intensity training. Facicula Educ. Fiz. şi Sport. 2014;2:57–67.
Kidd PM. Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. Altern. Med. Rev. 2010;15:199–222.
Kinuta K, Tanaka H, Moriwake T et al. Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads. Endocrinology. 2014;141:1317–1324.
Koundourakis NE, Androulakis NE, Malliaraki N, Margioris AN. Relation of vitamin D level to maximal oxygen uptake in adults. Am. J. Cardiol. 2011;107:1246–1249.
Krzywanski J, Mikulski T, Krysztofi ak H, Mlynczak M, Gaczynska E, Ziemba A. Seasonal Vitamin D Status in Polish Elite Athletes in Relation to Sun Exposure and Oral Supplementation. PLOS ONE. 2016;11(10):e0164395.
Lappe J, Cullen D, Haynatzki G, Recker R, Ahlf R, Thompson K. Calcium and Vitamin D Supplementation Decreases Incidence of Stress Fractures in Female Navy Recruits. Journal of Bone and Mineral Research. 2008;23(5):741-749.
Lovell G. Vitamin D status of females in an elite gymnastics program. Clin. J. Sport Med. 2008;18(2):159–161.
Lund D, Cornelison D. Enter the matrix: shape, signal and superhighway. FEBS
J. 2013;280:4089–4099.
Masterjohn C. Vitamin D toxicity redefi ned: vitamin K and the molecular mechanism. Med. Hypotheses. 2007;68:1026–1034.
Mauras N, Hayes V, Welch S, Rini A, Helgeson K, Dokler M et al. Testosterone Defi ciency in Young Men: Marked Alterations in Whole Body Protein Kinetics, Strength, and Adiposity1. The Journal of Clinical Endocrinology & Metabolism. 1998;83(6):1886-1892.
Medelli J, Lounana J, Menuet J, Shabani M, Cordero-MacIntyre Z. Is Osteopenia a Health Risk in Professional Cyclists? Journal of Clinical Densitometry. 2009;12(1):28-34.
Meekins M, Oberhelman S, Lee B, Gardner B, Cha S, Singh R [et al.] Pharmacokinetics of daily versus monthly vitamin D3supplementation in non-lactating women. European Journal of Clinical Nutrition. 2014;68(5):632-634.
Mowry D, Costello M, Heelan K. Association Between Bone Mineral Density, Percent Body Fat and Bone Serum Markers in Young Healthy Females. Medicine & Science in Sports & Exercise. 2008;40:S312-S313.
National Health and Medical Research Council. Nutrient reference values for Australia and New Zealand: Vitamin D. 2005.
Ogan D, Pritchett K. Vitamin D and the Athlete: Risks, Recommendations, and Benefi ts. Nutrients. 2013;5:1856–1868.
Pankaj P, Mageda M. Vitamin K defi ciency. Department of Gastroenterology, Winthrop University Hospital and SUNY-Stony Brook. 2008. P. 4-7.
Pilz S, Frisch S, Koertke H, Kuhn J, Dreier J, Obermayer-Pietsch B et al. Eff ect of Vitamin D Supplementation on Testosterone Levels in Men. Hormone and Metabolic Research. 2010;43(03):223-225.
Razavi M, Nazarali P, Hanachi P. The eff ect of an exercise programme and consumption of vitamin D on performance and respiratory indicators in patients with asthma. Sport Sciences for Health. 2011;6(2-3):89-92.
Reddy Vanga S, Good M, Howard P, Vacek J. Role of Vitamin D in Cardiovascular Health. The American Journal of Cardiology. 2010;106(6):798-805.
Ross A, Taylor C, Yaktine A, Valle H. Dietary reference intakes for calcium and Vitamin D. 1st ed. Washington: National Academies Press; 2011.
Sato Y, Iwamoto J, Kanoko T, Satoh K. Low-Dose Vitamin D Prevents Muscular Atrophy and Reduces Falls and Hip Fractures in Women after Stroke: A Randomized Controlled Trial. Cerebrovascular Diseases. 2005;20(3):187-192.
Slagmolen G V. Do Professional Soccer Players have a Vitamin D Status Supporting Optimal Performance in Winter time? Journal of Sports Medicine & Doping Studies. 2014;04(02).
Stachowicz M, Lebiedzińska A. The role of vitamin D in health preservation and exertional capacity of athletes. Postępy Higieny i Medycyny Doświadczalnej. 2016;70:637-643.
Stockton K, Mengersen K, Paratz J, Kandiah D, Bennell K. Eff ect of vitamin D supplementation on muscle strength: a systematic review and meta-analysis. Osteoporosis International. 2010.
Storlie DM, Pritchett K, Pritchett R, Cashman L. 12-Week vitamin D supplementation trial does not signifi cantly infl uence seasonal 25(OH)D status in male collegiate athletes. Int. J. Health Nutr. 2011;2:8-13.
Stratos I, Li Z, Herlyn P, Rotter R, Behrendt A, Mittlmeier T et al. Vitamin D Increases Cellular Turnover and Functionally Restores the Skeletal Muscle after Crush Injury in Rats. The American Journal of Pathology. 2013;182(3):895-904.
Sugimoto H, Shiro Y. Diversity and Substrate Specifi city in the Structures of Steroidogenic Cytochrome P450 Enzymes. Biological and Pharmaceutical Bulletin. 2012;35(6):818-823.
Tenforde A, Sayres L, Sainani K, Fredericson M. Evaluating the Relationship of Calcium and Vitamin D in the Prevention of Stress Fracture Injuries in the Young Athlete: A Review of the Literature. PM&R. 2010;2(10):945-949.
Todd J, Pourshahidi L, McSorley E, Madigan S, Magee P. Vitamin D: Recent Advances and Implications for Athletes. Sports Medicine. 2014;45(2):213-229.
Todd J, Madigan S, Pourshahidi K, McSorley E, Laird E, Healy M et al. Vitamin D Status and Supplementation Practices in Elite Irish Athletes: An Update from 2010/2011. Nutrients. 2016;8(8):485.
Tomlinson P, Joseph C, Angioi M. Eff ects of vitamin D supplementation on upper and lower body muscle strength levels in healthy individuals. A systematic review with meta-analysis. Journal of Science and Medicine in Sport. 2015;18(5):575-580.
Umhau J, George D, Heaney R, Lewis M, Ursano R, Heilig M et al. Low Vitamin D Status and Suicide: A Case-Control Study of Active Duty Military Service Members. PLoS ONE. 2013;8(1):e51543.
Urban R. Growth Hormone and Testosterone: Anabolic Eff ects on Muscle. Hormone Research in Paediatrics. 2011;76(s1):81-83.
Välimäki V, Alfthan H, Lehmuskallio E, Löyttyniemi E, Sahi T, Stenman U et al. Vitamin D Status as a Determinant of Peak Bone Mass in Young Finnish Men. The Journal of Clinical Endocrinology & Metabolism. 2004;89(1):76-80.
Välimäki V, Alfthan H, Ivaska K, Löyttyniemi E, Pettersson K, Stenman U et al. Serum Estradiol, Testosterone, and Sex Hormone-Binding Globulin as Regulators of Peak Bone Mass and Bone Turnover Rate in Young Finnish Men. The Journal of Clinical Endocrinology & Metabolism. 2004;89(8):3785-3789.
von Hurst P, Beck K. Vitamin D and skeletal muscle function in athletes. Current Opinion in Clinical Nutrition and Metabolic Care. 2014;17(6):539-545.
Wacker M, Holick M. Vitamin D—Eff ects on Skeletal and Extraskeletal Health and the Need for Supplementation. Nutrients. 2013;5(1):111-148.
Wehr E, Pilz S, Boehm B, März W, Obermayer-Pietsch B. Association of vitamin D status with serum androgen levels in men. Clinical Endocrinology. 2009.
Wentz LM, Eldred JD, Henry MD et al. Clinical relevance of optimizing vitamin D status in soldiers to enhance physical and cognitive performance. J. Spec. Oper. Med. 2014;14(1):58–66.
Wentz LM, Berry-Cabán CS, Wu Q, Eldred DJ. Vitamin D Correlation with Testosterone Concentration in Male US Soldiers and Veterans. J. Military and Veterans’ Health. 2016;24(3):17–23.
Willis K, Peterson N, Larson-Meyer D. Should We Be Concerned about the Vitamin D Status of Athletes?. International Journal of Sport Nutrition and Exercise Metabolism. 2008;18(2):204-224.
Larson-Meyer D, Willis, Smith, Broughton. Vitamin D status and biomarkers of infl ammation in runners. Open Access Journal of Sports Medicine. 2012;:35.
Working Group of the Australian and New Zealand Bone and Mineral Society, Endocrine Society of Australia and Osteoporosis Australia. Vitamin D and adult bone health in Australia and New Zealand: A position statement. MJA. 2005;182(6): 281-285.
Zittermann A. Vitamin D in preventive medicine: are we ignoring the evidence?. British Journal of Nutrition. 2003;89(05):552.
Загрузки
Опубликован
Выпуск
Раздел
Лицензия
Copyright (c) 2018 Наука в олимпийском спорте
Это произведение доступно по лицензии Creative Commons «Attribution-NonCommercial» («Атрибуция — Некоммерческое использование») 4.0 Всемирная.
Все статьи открытого доступа распространяются под терминами Creative Commons Attribution-NonCommercial 4.0 International License , которая позволяет другим людям перерабатывать, поправлять и брать статьи за основу для производных в некоммерческих целях. Новые произведения должны размещаться с указанием авторства и распространяться на некоммерческой основе, лицензирование производных на тех же условиях не обязательно.